Asthenozoospermia: Causes and Infertility Solutions

May 15, 2024
6 min read
By Hera Fertility
Are you experiencing difficulty with conception despite several attempts? Asthenozoospermia, a condition characterized by reduced sperm motility, could be the underlying cause affecting your fertility. Asthenozoospermia affects approximately 18.7% to 63.13% of infertile men. Understanding the factors contributing to asthenozoospermia enables couples to seek appropriate fertility solutions and improve their chances of conception.

Are you experiencing difficulty with conception despite several attempts? Asthenozoospermia, a condition characterized by reduced sperm motility, could be the underlying cause affecting your fertility.

Asthenozoospermia affects approximately 18.7% to 63.13% of infertile men.

Understanding the factors contributing to asthenozoospermia enables couples to seek appropriate fertility solutions and improve their chances of conception.

What is Asthenozoospermia?

Asthenozoospermia is a medical condition where sperm have reduced motility, making it difficult for them to swim effectively toward the egg for fertilization. This condition is one of the leading causes of male infertility.

Causes of Asthenozoospermia

Asthenozoospermia results from multiple factors, including genetic abnormalities, hormonal imbalances, infections, and lifestyle choices.

For instance, genetic disorders and mutations can impair sperm motility, affecting its ability to fertilize an egg. In addition to genetic factors, hormonal imbalances involving testosterone or thyroid hormones can compromise sperm quality and function.

Genetic Factors

Genetic factors significantly impact sperm motility, which is crucial for successful fertilization. Variations or mutations in specific genes can interfere with the structure and movement of sperm, leading to asthenozoospermia.

Studies have identified conditions such as Klinefelter syndrome and Y chromosome microdeletions as contributors to decreased sperm motility. These genetic abnormalities disrupt normal sperm development and function.

Addressing genetic factors: Genetic counseling and testing can help identify potential genetic issues, guiding effective treatment plans.

Hormonal Imbalances

Hormonal imbalances can significantly disrupt sperm development and function, impacting motility and overall fertility:

  • Testosterone Imbalance: Essential for sperm production; low levels can impair motility
  • Follicle-Stimulating Hormone (FSH): Regulates sperm development; imbalances can reduce sperm count
  • Luteinizing Hormone (LH): Stimulates testosterone production; imbalances can hinder sperm quality
  • Thyroid Hormones: Regulate overall metabolism; thyroid imbalances can negatively affect sperm motility
  • Hyperprolactinemia: Excessive prolactin levels can suppress reproductive hormones
  • Hypogonadism: Lowered gonadal function can lead to reduced sperm production and mobility

Infections

Infections can significantly impact sperm health, leading to asthenozoospermia:

Sexually transmitted infections (STIs) such as Chlamydia, Gonorrhea, and Herpes can cause inflammation and damage to the reproductive tract, affecting sperm motility.

Beyond STIs, infections in the prostate (prostatitis) and epididymis (epididymitis) can also contribute to decreased sperm movement. These localized infections create a hostile environment for sperm, reducing their viability and motility.

Symptoms of Asthenozoospermia

Asthenozoospermia itself typically doesn't present with any noticeable symptoms. The condition usually comes to light during an investigation into infertility when a semen analysis is performed.

Infertility Challenges

The primary symptom is difficulty conceiving. Couples may experience prolonged periods of unsuccessful attempts at conceiving, which can take an emotional and psychological toll.

Physical Discomfort

Some men may experience:

  • Pain, swelling, or discomfort in the testicles
  • Symptoms from underlying infections
  • Inflammation affecting overall genital health

Diagnosis of Asthenozoospermia

Asthenozoospermia diagnosis primarily involves a semen analysis to evaluate sperm motility.

Semen Analysis

A semen analysis is an essential diagnostic tool that involves:

  • Collecting a semen sample (usually through masturbation)
  • Laboratory analysis of sperm count, motility, and morphology
  • Screening for infections, pH levels, and white blood cells
  • Advanced computerized systems to analyze sperm movement patterns

Treatment Options

The treatment of asthenozoospermia depends on its underlying causes and can vary significantly.

Lifestyle Changes

Promoting lifestyle changes is essential for addressing asthenozoospermia:

  • Balanced diet: Rich in antioxidants, fruits, vegetables, whole grains, and lean proteins
  • Regular exercise: Crucial for overall health and sperm function
  • Stress reduction: Managing stress levels through relaxation techniques
  • Eliminate harmful habits: Avoiding smoking, excessive alcohol, and recreational drugs
  • Environmental factors: Minimizing exposure to toxins and avoiding excessive heat

Medical Interventions

Medical interventions can offer significant assistance:

  • Medications: Addressing hormonal imbalances affecting sperm motility
  • Antibiotics: Treating underlying infections
  • Surgical procedures: Repairing varicoceles or other structural issues
  • Advanced techniques: Microsurgical epididymal sperm aspiration (MESA)

Assisted Reproductive Technologies (ART)

ART represents a vital avenue for couples facing asthenozoospermia:

  • Intrauterine Insemination (IUI): Sperm is directly inserted into the uterus
  • In-Vitro Fertilization (IVF): Egg and sperm are combined outside the body
  • Intracytoplasmic Sperm Injection (ICSI): A single sperm is injected directly into an egg

These procedures can help overcome the limitations posed by natural conception challenges, offering new hope to couples affected by asthenozoospermia.